顏承云:
男,,桂林醫(yī)學(xué)院藥學(xué)院藥劑藥動教研室教授,,沈陽藥科大學(xué)藥劑學(xué)專業(yè)博士研究生,,日本京都藥科大學(xué)生物藥劑室博士后,美國俄亥俄州立大學(xué)藥學(xué)院藥劑室訪問學(xué)者,。
主要研究方向:1.藥用新輔料應(yīng)用及腫瘤靶向傳遞系統(tǒng)研究;2.難吸收藥物黏膜吸收的研究,。
主要科研成果:主持日本21st Century COE Program 1項,;主持國家自然科學(xué)基金3項、主持區(qū)(省)自然基金4項、教育廳重點(diǎn)實驗室課題1項,;參與其它部,、廳、局級項目多項,;在國內(nèi)外著名醫(yī)藥刊物上發(fā)表論文30余篇,,其中第一作者SCI論文13篇;獲得發(fā)明型專利1項,;獲市科技進(jìn)步一等獎1項,;出版專著1部。
代表論文:
1.Chengyun Yan*, Jiwei Gu,,Yuan Zhang , Kailun Ma, Robert J. Lee.
Yuan Zhang. Efficient delivery of the Bcl-2 antisense oligonucleotide G3139 via nucleus-targeted aCD33-NKSN nanoparticles. INT J PHARMACEUT. 2022,
(625):122074.
2.Chengyun Yan*, Weiguo Shi, Jiwei Gu,,Robert J. Lee, Yuan Zhang . Design of a Novel Nucleus-Targeted NLS-KALA-SA Nanocarrier to Delivery Poorly Water-Soluble Anti-Tumor Drug for Lung Cancer Treatment. J Pharm Sci. 2021, 110(6):2432-2441.
3.Chengyun Yan*, Robert J. Lee. Tat Tagged and Folate Modified N-succinyl-
chitosan (Tat-Suc-FA)Self-assembly Nanoparticle for Therapeutic Delivery
OGX-011 to A549 Cells. Mol. Pharmaceutics. 2017, 14 (6): 1898–1905
4.Chengyun Yan*,Jiwei Gu. Improved intestinal absorption of water-soluble drugs by acetylation of G2 PAMAM dendrimer nanocomplexes in rat. Drug Deliv.and Transl.Res. 2017, 7(3): 408- 415.
5.Cheng-yun Yan*, Akira Yamamoto. Synthesis of Tat tagged and folate modified N-succinyl-chitosanself-assembly nanoparticles as a novel gene vector. International Journal of Biological Macromolecules. 2015, (72) 751–756