顏承云:
男,,桂林醫(yī)學(xué)院藥學(xué)院藥劑藥動(dòng)教研室教授,,沈陽(yáng)藥科大學(xué)藥劑學(xué)專業(yè)博士研究生,,日本京都藥科大學(xué)生物藥劑室博士后,美國(guó)俄亥俄州立大學(xué)藥學(xué)院藥劑室訪問(wèn)學(xué)者,。
主要研究方向:1.藥用新輔料應(yīng)用及腫瘤靶向傳遞系統(tǒng)研究,;2.難吸收藥物黏膜吸收的研究。
主要科研成果:主持日本21st Century COE Program 1項(xiàng),;主持國(guó)家自然科學(xué)基金3項(xiàng),、主持區(qū)(省)自然基金4項(xiàng)、教育廳重點(diǎn)實(shí)驗(yàn)室課題1項(xiàng),;參與其它部,、廳、局級(jí)項(xiàng)目
多項(xiàng),;在國(guó)內(nèi)外著名醫(yī)藥刊物上發(fā)表論文30余篇,,其中第一作者SCI論文13篇;獲得發(fā)明型專利1項(xiàng),;獲市科技進(jìn)步一等獎(jiǎng)1項(xiàng),;出版專著1部。
代表論文:
1.Chengyun Yan*, Jiwei Gu,,Yuan Zhang , Kailun Ma, Robert J. Lee.
Yuan Zhang. Efficient delivery of the Bcl-2 antisense oligonucleotide G3139 via nucleus-targeted aCD33-NKSN nanoparticles. INT J PHARMACEUT. 2022,
(625):122074.
2.Chengyun Yan*, Weiguo Shi, Jiwei Gu,,Robert J. Lee, Yuan Zhang . Design of a Novel Nucleus-Targeted NLS-KALA-SA Nanocarrier to Delivery Poorly Water-Soluble Anti-Tumor Drug for Lung Cancer Treatment. J Pharm Sci. 2021, 110(6):2432-2441.
3.Chengyun Yan*, Robert J. Lee. Tat Tagged and Folate Modified N-succinyl-
chitosan (Tat-Suc-FA)Self-assembly Nanoparticle for Therapeutic Delivery
OGX-011 to A549 Cells. Mol. Pharmaceutics. 2017, 14 (6): 1898–1905
4.Chengyun Yan*,Jiwei Gu. Improved intestinal absorption of water-soluble drugs
by acetylation of G2 PAMAM dendrimer nanocomplexes in rat. Drug Deliv.and
Transl.Res. 2017, 7(3): 408- 415.
5.Cheng-yun Yan*, Akira Yamamoto. Synthesis of Tat tagged and folate modified N-succinyl-chitosanself-assembly nanoparticles as a novel gene vector. International Journal of Biological Macromolecules. 2015, (72) 751–756